CXCR4 ELISA Kit for Pig(Sus scrofa) | EIAab.comCXCR4 ELISA Kit for Pig(Sus scrofa)

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Index > Protein center > CXCR4(Gene name) > Pig

CXCR4 (Gene name),

C-X-C chemokine receptor type 4 (Protein name ), CXCR4_PIG from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

CXCR4;

Protein name:

C-X-C chemokine receptor type 4(CXC-R4;CXCR-4);

Alternative:

CD:

CD184;

Organism:

Pig (Sus scrofa).

General Annotation

Sub Unit:

Monomer (By similarity). Can form dimers (By similarity). Interacts with CD164. Interacts with ARRB2; the interaction is dependent on the C-terminal phosphorylation of CXCR4 and allows activation of MAPK1 and MAPK3. Interacts with ARRC; the interaction is dependent on the C-terminal phosphorylation of CXCR4 and modulates calcium mobilization. Interacts (via the cytoplasmic C-terminal) with ITCH (via the WW domains I and II); the interaction, enhanced by CXCL12, ubiquitinates CXCR4 and leads to its degradation. Interacts with extracellular ubiquitin; the interaction enhances intracellular calcium ions and reduces cellular cAMP levels.

Function:

Receptor for the C-X-C chemokine CXCL12/SDF-1 that transduces a signal by increasing intracellular calcium ion levels and enhancing MAPK1/MAPK3 activation. Acts as a receptor for extracellular ubiquitin; leading to enhanced intracellular calcium ions and reduced cellular cAMP levels. Involved in hematopoiesis and in cardiac ventricular septum formation. Also plays an essential role in vascularization of the gastrointestinal tract, probably by regulating vascular branching and/or remodeling processes in endothelial cells. Involved in cerebellar development. In the CNS, could mediate hippocampal-neuron survival.

Subcellular Location:

Cell membrane Multi-pass membrane protein In unstimulated cells, diffuse pattern on plasma membrane. On agonist stimulation, colocalizes with ITCH at the plasma membrane where it becomes ubiquitinated.

Protein Attributes:

Sequence length:

353

Sequence:

50:

100:

150:

200:

250:

300:

350:

353:

HSS

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

KEGG:

ssc:396659

String:

Q764M9

Pfam:

PF00001

UniGene:

Ssc.7176

STRING:

9823.ENSSSCP00000016630

Uniprot:

Q764M9

FOR

ELISA Kit for Pig CXC-R4

Cat.:

E2170h

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Manual:

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Packing:

96T

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ELISA Kit for Pig CXC-R4

Cat.:

E2170p

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Packing:

96T

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ELISA Kit for Pig CXC-R4

Cat.:

E2170b

Price:

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MSDS:

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Packing:

96T

ELISA Kit for Pig CXC-R4

Cat.:

E2170m

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MSDS:

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Packing:

96T

ELISA Kit for Pig CXC-R4

Cat.:

E2170d

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MSDS:

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Packing:

96T

ELISA Kit for Pig CXC-R4

Cat.:

E2170r

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MSDS:

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Packing:

96T

CLIA Kit for Pig CXC-R4

Cat.:

U2170p

Price:

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MSDS:

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Packing:

96T

CLIA Kit for Pig CXC-R4

Cat.:

U2170b

Price:

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MSDS:

Please sign in first.

Packing:

96T

CLIA Kit for Pig CXC-R4

Cat.:

U2170m

Price:

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MSDS:

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Packing:

96T

CLIA Kit for Pig CXC-R4

Cat.:

U2170h

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Manual:

Looking for manual.

MSDS:

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Packing:

96T

Range:

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CLIA Kit for Pig CXC-R4

Cat.:

U2170r

Price:

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MSDS:

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Packing:

96T

CLIA Kit for Pig CXC-R4

Cat.:

U2170d

Price:

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Packing:

96T

Polyclonal Antibody for Pig CXC-R4

Cat.:

P2170Rb-r

Price:

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Packing:

40ug/0.2ml

Polyclonal Antibody for Pig CXC-R4

Cat.:

P2170Rb-h

Price:

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Packing:

40ug/0.2ml

Polyclonal Antibody for Pig CXC-R4

Cat.:

P2170Rb-m

Price:

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Packing:

40ug/0.2ml

Monoclonal Antibody for Pig CXC-R4

Protein for Pig CXC-R4

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

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References

1.

"Porcine heart CXCR4 sequence."
Lin H. , Canty J.M. , Lee T.
Submitted (2005-07) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
tissue: Heart.
2.

"PEDE (Pig EST Data Explorer): construction of a database for ESTs derived from porcine full-length cDNA libraries."
Uenishi H. , Eguchi T. , Suzuki K. , Sawazaki T. , Toki D. , Shinkai H. , Okumura N. , Hamasima N. , Awata T.
Nucleic Acids Res.32:D484-D488(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]

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